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The Science Behind Soft Baby Skin: Understanding Caseosa Vernix


Skin health and immunity begin long before birth. The skin, our first line of defense against external threats, begins its development in the womb. This article explores the science behind the soft, protective layer known as Vernix Caseosa and its importance for newborns.

The Wonderful World of Epidermal Immunity

The history of epidermal immunity is truly fascinating. It begins in utero, where the skin barrier originates from the ectoderm. This barrier undergoes a series of carefully coordinated biological processes, such as periderm formation, keratinocyte differentiation, proliferation, cornification and maturation. The end result? A functional epidermis ready to protect the newborn.

Vernix Caseosa: Nature’s protective cocoon

Vernix Caseosa, Vernixa, baby, newborn, sensitive skin, infant, birth, cosmetic products, Lipidic V

One of the most remarkable elements of this epidermal development is the Vernix Caseosa. This substance is produced by epidermal cells that combine with sebaceous lipids. During the final stages of pregnancy, it covers the fetus, probably creating the right conditions for cornification. Think of it as the baby’s natural moisturizer and shield in the womb.

Real-life example 1: Have you ever noticed the creamy white substance on a newborn baby’s skin? This is Vernix Caseosa. It’s not something to be washed off immediately after birth; it’s nature’s way of providing initial skin protection.

Real-life example 2: Many traditional cultures around the world leave Vernix Caseosa on the newborn for several days, in recognition of its protective properties.

Transition after birth

Once the baby is born, there’s a dramatic change from an aquatic environment to a dry, gaseous one. The skin’s epidermal barrier begins to adapt within a few hours. It shows signs of reduced dehydration and less cohesion in the stratum corneum (the outermost layer of the skin). Over the next 2-3 months, this barrier undergoes significant changes, differentiating itself considerably from stable adult skin.

Real Example 3: That’s why the skin of newborn babies is so soft and delicate. It is still adapting to the outside world, hence the importance of using gentle care products.

The role of the Natural Hydration Factor (NHF)

An interesting observation is that the natural hydration factor (NHF), which results from filaggrin treatment, is higher in infants than in adults. This indicates that neonatal skin intrinsically offers immunity and protection against environmental factors. It also highlights the rapid development of the skin after birth.

Real-life example 4: Have you ever wondered why babies’ skin is so soft and moisturized? High levels of FNH play a crucial role in maintaining this texture.

Vernixa®: Inspired by Nature

At Vernixa®, we’ve harnessed the power of Vernix Caseosa to create our patented ingredient, Lipidic V®. Our 100% natural-origin products, such as Vernixa® Hydra Lavant and Vernixa® Hydra Crème, are formulated with this bio-inspired ingredient. They aim to provide skin with the same natural protection and hydration that Vernix Caseosa offers newborns.

Real-life example 5: Over 95% of customers noticed a significant improvement in skin hydration and texture after using our products, reflecting the natural benefits of Vernix Caseosa.


Understanding the science behind Vernix Caseosa and its role in neonatal skin health is essential. Not only does this highlight the wonders of nature, it also underlines the importance of science-backed skincare products. At Vernixa®, we’re committed to combining science and luxury, to offer your skin the very best.

Reference: Immunity and Epidermal Function: Origins in Neonatal Skin

Who we are

We've created the perfect routine for cleansing and moisturizing baby skin.

Our products are:

  • Made in France 🇫🇷
  • 100% ingredients of natural origin 🌱
  • Approved by pediatricians and dermatologists
  • Tested under pediatric and dermatological supervision
  • Adapted from birth
  • For sensitive, dry, atopic skin
  • Formulated by Prof. Dr. Nabila Belhaj (Ph.D)
  • Compatible with pregnancy and breastfeeding
  • Made with our patented active ingredient, Lipidic V®.

Customer Reviews

RO** Ch*********
RO** Ch*********
Vernixa Hydra Wash
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I use Hydra Lavant daily to cleanse my four-year-old daughter: a real sensation of care on application, a delicate foam, a product that rinses off easily and leaves a perceptible protective film. Even after drying, the skin is supple and emollient. My daughter no longer feels any tightness, even in this winter season. As for me, I use it to remove my make-up in the shower, it's super gentle on the face and removes make-up residue without aggression. At last, a cleanser in which every ingredient has added value, and which truly respects fragile skin!
Dj****** C
Dj****** C
Vernixa Hydra Cream
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My skin is better cared for As someone who neglected skincare, Vernixa was a revelation. The light application has simplified my routine, leaving my skin feeling well cared for and radiant.
Vernixa Hydra Cream
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As someone with extremely sensitive skin, I'm normally very reluctant to use them. But the Vernixa cream has changed all that! Its natural composition soothed my skin without causing irritation.

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